Sodium Erythorbate
Sodium ascorbate is an organic matter, chemical formula for C6H7O6Na, white to slightly yellowish white crystalline powder or
particles, odourless, slightly salty taste. Decomposition temperature of 218 ° C, dry state is more stable, the colour deepens when
exposed to light, moisture absorption and slow oxidative decomposition in aqueous solution. More soluble in water than ascorbic
acid (62g/100mL), 10% aqueous solution pH about 7.5.
| Specification of Sodium Erythorbate |
| Items |
Standards |
| Characteristics |
White crystalline solid |
| Identification |
Passes test A,B,C |
| Assay % |
98.0 min |
| Oxalate |
Passes test |
| Specific rotation [α]25D |
+95.0° ~ +98.0° |
| Mercury mg/kg |
1 max |
| Arsenic mg/kg |
3 max |
| Lead mg/kg |
2 max |
| Loss on drying % |
0.25 max |
| PH Value |
5.5~8.0 |
| Conclusion |
The product conforms to the standard of E316 |
[Stability] The aqueous solution is unstable and can be relatively stable by air pH greater than 6.0 on exposure to air and ignition
it gradually darkens. Ascorbic acid oxidises rapidly when exposed to light and gradually darkens, however, slight colouring does
not impair the therapeutic activity of Ascorbic Acid Injection. The solution of ascorbic acid is rapidly oxidised in air and the drug in
alkaline media should be protected from air and light. At concentrations greater than 100 mg/ml ascorbic acid may undergo
decomposition with the production of carbon dioxide. Due to the increased pressure can be stored for long periods of time, be
careful opening ampoules containing sodium ascorbate.
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